Translational Medicine Specialist, Antigen Map

    • Job Tracking ID: 180008
    • Job Location: Seattle, WA
    • Job Level: Any
    • Level of Education: Any
    • Job Type: Full-Time/Regular
    • Date Updated: April 24, 2018
    • Years of Experience: Not Applicable
    • Starting Date: ASAP
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Job Description:

ARE YOU ADAPTIVE? Based in Seattle, Adaptive’s Antigen Map team is working jointly with Microsoft to develop a blood test that uses the T-cell repertoire to diagnose malignant, autoimmune and infectious diseases.  We are learning how to read the T cell repertoire by combining Adaptive’s core next generation T-cell receptor (TCR) sequencing with cellular immunology assays. We identify antigen-specific TCRs at an unprecedented scale, and utilize the power of machine learning to extend our understanding across trillions of TCRs. Our goal is to produce and deploy TCR-based diagnostics, and ultimately to map all the antigens recognized by human T cells to create a universal blood-based diagnostic. #BeingAdaptive

 Position Overview

The Translational Medicine Specialist is a core member of the Adaptive Antigen Map team and is responsible for advancing Adaptive’s scientific insights into viable clinical products. This leader will develop and execute translational strategies for furthering the development of Adaptive’s next diagnostic products, with opportunities in infectious disease, autoimmunity and oncology. The successful candidate will work cross-functionally to develop a clinical development strategy across potential applications in alignment with Antigen Map team leadership. The Translational Medicine Specialist will also develop and manage clinical protocols and validation in clinical data sets that meet regulatory requirements.

Key Responsibilities

  • Serve as the dedicated translational medicine lead for the Antigen Map project
  • Help develop strategy for the Antigen Map program to ensure alignment between R&D objectives and unmet medical need
  • Support clinical development and validation of new diagnostic products
  • Develop and lead Adaptive-sponsored clinical protocols to test key hypotheses
  • Represent Adaptive externally and deliver scientific presentations
  • Support cross-functional teams to broaden existing and secure new clinical opportunities
  • Serve as a clinical resource to internal stakeholders such as business development, research, computational biology, marketing and sales

Experience and Skills:

  • MD with a minimum 10 years of experience, with a minimum 2 years of experience in translational and clinical research
  • Deep understanding of translational research/medicine and clinical diagnostics
  • Demonstrated experience in the application various scientific technologies into translational research strategies
  • Demonstrated scientific acumen and mechanistic understanding of disease biology
  • Working knowledge of FDA guidance for the Dx and Rx industries
  • Ability to manage multiple projects and engage with diverse stakeholders in a dynamic environment within tight timelines
  • Ability to think quantitatively, interpret clinical data and interact with computational biologists and biostatisticians
  • Strong interpersonal and presentation skills, good judgment and ability to communicate with a diverse range of individuals
  • Excited about an early stage company environment and driven to make a difference
  • Strong work ethic with expectation of excellence from self and others