Senior Research Associate, TCR Discovery Team

    • Job Tracking ID: 170083
    • Job Location: South San Francisco, CA
    • Job Level: Any
    • Level of Education: Any
    • Job Type: Full-Time/Regular
    • Date Updated: December 14, 2017
    • Years of Experience: Any
    • Starting Date: ASAP
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Job Description:

About the TCR Discovery Team

ARE YOU ADAPTIVE? Based in South San Francisco, Adaptive’s Discovery team is developing a world-class high-throughput TCR discovery platform. Our mission is to resolve the T cell repertoire by combining Adaptive’s core next generation TCR sequencing with cellular immunology assays to identify antigen-specific TCRs at an unprecedented scale. Our goal is to produce clinically useful TCR-based biomarkers and therapeutics, and ultimately to map the universe of antigens recognized by human T cells. #BeingAdaptive


Position Overview

Adaptive is looking for an outstanding researcher to join our discovery team based in South San Francisco. At Adaptive you will be working with a dynamic and cross-functional team that is focused on identification of TCR-based therapeutic candidates and clinically useful biomarkers. You will implement a variety of cellular assays aimed at identifying and characterizing T cells, including assays measuring T cell antigen specificity and function. You will also coordinate general lab maintenance tasks such as ordering reagents, restocking lab consumables, and regular upkeep of lab equipment.



  • Develop and implement a variety of complex cellular assays primarily aimed at measuring T cell responses to antigen
  • Manage cell stock inventory by processing and cryopreserving cells from a variety of sources including leukapheresis products
  • Culture and maintain primary cells and cells lines
  • Coordinate day-to-day lab activities including equipment maintenance, reagent orders, restocking consumables, etc.
  • Work and communicate with group members in a dynamic and fast-paced environment in order to accomplish goals

Experience and Skills:

  • B.Sc in biological sciences
  • 5+ years lab experience in immunology, cellular immunology or related fields
  • Cell culture experience with both human primary cells and cell lines
  • Experience with multiparametric flow cytometry
  • Familiarity with BSL-2 protocols and best practices
  • Knowledge of T cells and TCRs is a plus
  • Experience with conventional T cell assays and read-outs (proliferation, activation, antigen-specificity, cytotoxicity) is a plus


Salary is commensurate with experience and qualifications. Excellent benefits package including employer paid medical, dental, vision, vacations and holidays for eligible positions.

Adaptive Biotechnologies Corp. is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners whom have been contracted by a member of our Human Resources team to collaborate with us. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.